"Surfing Uncertainty" on Autism (and Schizophrenia)

Scott Alexander got pretty excited back in September about Andy Clark's "Surfing Uncertainty" (in this post) - but that's because he's a psychiatrist and Clark's model has some insightful things to say about both Autism (Asperger's Syndrome) and Schizophrenia.

Amazon link

I read the book and found Clark's approach (that biological agents, aka 'animals', cognitively function through a combination of top-down model-based prediction and bottom-up sensor-based verification) highly plausible, though not that new. Still he pushes the model quite a way - the details are instructive.

My main problem with the text is that the proposed model is really an architectural/engineering one, yet Clark is a philosopher. He writes in that over-abstract, bloated and padded style which people like Daniel Dennett have made so famous.

Somewhere in there, good ideas are trying to extricate themselves from the gloop.

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Anyway, here's how Scott Alexander, channelling Andy Clark, talks about Autism.

"Various research in the PP [Predictive Processing] tradition has coalesced around the idea of autism as an unusually high reliance on bottom-up rather than top-down information, leading to “weak central coherence” and constant surprisal as the sensory data fails to fall within pathologically narrow confidence intervals.

Autistic people classically can’t stand tags on clothing – they find them too scratchy and annoying. Remember the example from Part III about how you successfully predicted away the feeling of the shirt on your back, and so manage never to think about it when you’re trying to concentrate on more important things? Autistic people can’t do that as well.

Even though they have a layer in their brain predicting “will continue to feel shirt”, the prediction is too precise; it predicts that next second, the shirt will produce exactly the same pattern of sensations it does now. But realistically as you move around or catch passing breezes the shirt will change ever so slightly – at which point autistic people’s brains will send alarms all the way up to consciousness, and they’ll perceive it as “my shirt is annoying”.

Or consider the classic autistic demand for routine, and misery as soon as the routine is disrupted. Because their brains can only make very precise predictions, the slightest disruption to routine registers as strong surprisal, strong prediction failure, and “oh no, all of my models have failed, nothing is true, anything is possible!”

Compare to a neurotypical person in the same situation, who would just relax their confidence intervals a little bit and say “Okay, this is basically 99% like a normal day, whatever”. It would take something genuinely unpredictable – like being thrown on an unexplored continent or something – to give these people the same feeling of surprise and unpredictability."

As an AQ high-scorer, I relate to this. In many a social situation I'm walking on eggshells, never quite knowing how people will respond. I'll say something which seems amusing within my own private model of the subject of discourse, only to be met with incomprehension - or worse, consternation - as my poor unconscious predictive model of other people's likely response fails again.

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The very next section (11) summarises the story on Schizophrenia:

"Schizophrenia. Converging lines of research suggest this also involves weak priors, apparently at a different level to autism and with different results after various compensatory mechanisms have had their chance to kick in.

One especially interesting study asked neurotypicals and schizophrenics to follow a moving light, much like the airplane video in Part III above. When the light moved in a predictable pattern, the neurotypicals were much better at tracking it; when it was a deliberately perverse video specifically designed to frustrate expectations, the schizophrenics actually did better.

This suggests that neurotypicals were guided by correct top-down priors about where the light would be going; schizophrenics had very weak priors and so weren’t really guided very well, but also didn’t screw up when the light did something unpredictable. ...

The exact route from this sort of thing to schizophrenia is really complicated, and anyone interested should check out Section 2.12 and the whole of Chapter 7 from the book. But the basic story is that it creates waves of anomalous prediction error and surprisal, leading to the so-called “delusions of significance” where schizophrenics believe that eg the fact that someone is wearing a hat is some sort of incredibly important cosmic message.

Schizophrenics’ brains try to produce hypotheses that explain all of these prediction errors and reduce surprise – which is impossible, because the prediction errors are random. This results in incredibly weird hypotheses, and eventually in schizophrenic brains being willing to ignore the bottom-up stream entirely – hence hallucinations.

All this is treated with antipsychotics, which antagonize dopamine, which – remember – represents confidence level. So basically the medication is telling the brain “YOU CAN IGNORE ALL THIS PREDICTION ERROR, EVERYTHING YOU’RE PERCEIVING IS TOTALLY GARBAGE SPURIOUS DATA” – which turns out to be exactly the message it needs to hear.

An interesting corollary of all this – because all of schizophrenics’ predictive models are so screwy, they lose the ability to use the “adjust away the consequences of your own actions” hack discussed in Part 5 of this section.

That means their own actions don’t get predicted out, and seem like the actions of a foreign agent. This is why they get so-called “delusions of agency”, like “the government beamed that thought into my brain” or “aliens caused my arm to move just now”. And in case you were wondering – yes, schizophrenics can tickle themselves."

My overall take-home message from this book was that tabula rasa, blank slate paradigms of so much contemporary AI may suffice for crafting smart and powerful classificatory tools, but they won't hack it when we try to build socially-competent agents. In facial recognition and playing Go we're already superhuman; chatbots not so much.

"Surfing Uncertainty" - Andy Clark

Amazon link

Scott Alexander at SlateStarCodex has a glowing review of Andy Clark's recent book.

"Sometimes I have the fantasy of being able to glut myself on Knowledge. I imagine meeting a time traveler from 2500, who takes pity on me and gives me a book from the future where all my questions have been answered, one after another. What’s consciousness? That’s in Chapter 5. How did something arose out of nothing? Chapter 7. It all makes perfect intuitive sense and is fully vouched by unimpeachable authorities. I assume something like this is how everyone spends their first couple of days in Heaven, whatever it is they do for the rest of Eternity.

"And every so often, my fantasy comes true. Not by time travel or divine intervention, but by failing so badly at paying attention to the literature that by the time I realize people are working on a problem it’s already been investigated, experimented upon, organized into a paradigm, tested, and then placed in a nice package and wrapped up with a pretty pink bow so I can enjoy it all at once.

"The predictive processing model is one of these well-wrapped packages. Unbeknownst to me, over the past decade or so neuroscientists have come up with a real theory of how the brain works – a real unifying framework theory like Darwin’s or Einstein’s – and it’s beautiful and it makes complete sense.

"Surfing Uncertainty isn’t pop science and isn’t easy reading. Sometimes it’s on the border of possible-at-all reading. Author Andy Clark (a professor of logic and metaphysics, of all things!) is clearly brilliant, but prone to going on long digressions about various esoteric philosophy-of-cognitive-science debates."

It's prose like this which confirms what a great writer Scott Alexander is.

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The underlying thesis of Surfing Uncertainty is certainly not news to AI researchers.

"We never see the world as our retina sees it. In fact, it would be a pretty horrible sight: a highly distorted set of light and dark pixels, blown up toward the center of the retina, masked by blood vessels, with a massive hole at the location of the “blind spot” where cables leave for the brain; the image would constantly blur and change as our gaze moved around.

"What we see, instead, is a three-dimensional scene, corrected for retinal defects, mended at the blind spot, stabilized for our eye and head movements, and massively reinterpreted based on our previous experience of similar visual scenes. All these operations unfold unconsciously—although many of them are so complicated that they resist computer modeling. For instance, our visual system detects the presence of shadows in the image and removes them. ...

"Predictive processing begins by asking: how does this happen? By what process do our incomprehensible sense-data get turned into a meaningful picture of the world?

"The key insight: the brain is a multi-layer prediction machine. All neural processing consists of two streams: a bottom-up stream of sense data, and a top-down stream of predictions. These streams interface at each level of processing, comparing themselves to each other and adjusting themselves as necessary.

"The bottom-up stream starts out as all that incomprehensible light and darkness and noise that we need to process. It gradually moves up all the cognitive layers that we already knew existed – the edge-detectors that resolve it into edges, the object-detectors that shape the edges into solid objects, et cetera.

"The top-down stream starts with everything you know about the world, all your best heuristics, all your priors, everything that’s ever happened to you before – everything from “solid objects can’t pass through one another” to “e=mc²” to “that guy in the blue uniform is probably a policeman”. It uses its knowledge of concepts to make predictions – not in the form of verbal statements, but in the form of expected sense data. It makes some guesses about what you’re going to see, hear, and feel next, and asks “Like this?”

"These predictions gradually move down all the cognitive layers to generate lower-level predictions. If that uniformed guy was a policeman, how would that affect the various objects in the scene? Given the answer to that question, how would it affect the distribution of edges in the scene? Given the answer to that question, how would it affect the raw-sense data received?

"Both streams are probabilistic in nature. The bottom-up sensory stream has to deal with fog, static, darkness, and neural noise; it knows that whatever forms it tries to extract from this signal might or might not be real. For its part, the top-down predictive stream knows that predicting the future is inherently difficult and its models are often flawed. So both streams contain not only data but estimates of the precision of that data.

"A bottom-up percept of an elephant right in front of you on a clear day might be labelled “very high precision”; one of a a vague form in a swirling mist far away might be labelled “very low precision”. A top-down prediction that water will be wet might be labelled “very high precision”; one that the stock market will go up might be labelled “very low precision”.

"As these two streams move through the brain side-by-side, they continually interface with each other. Each level receives the predictions from the level above it and the sense data from the level below it. Then each level uses Bayes’ Theorem to integrate these two sources of probabilistic evidence as best it can. This can end up a couple of different ways.

"First, the sense data and predictions may more-or-less match. In this case, the layer stays quiet, indicating “all is well”, and the higher layers never even hear about it. The higher levels just keep predicting whatever they were predicting before.

"Second, low-precision sense data might contradict high-precision predictions. The Bayesian math will conclude that the predictions are still probably right, but the sense data are wrong. The lower levels will “cook the books” – rewrite the sense data to make it look as predicted – and then continue to be quiet and signal that all is well. The higher levels continue to stick to their predictions.

"Third, there might be some unresolvable conflict between high-precision sense-data and predictions. The Bayesian math will indicate that the predictions are probably wrong. The neurons involved will fire, indicating “surprisal” – a gratuitously-technical neuroscience term for surprise. The higher the degree of mismatch, and the higher the supposed precision of the data that led to the mismatch, the more surprisal – and the louder the alarm sent to the higher levels."

Alexander's review continues to explain the theory outlined at greater length in Clark's book, and then moves on to applications. I was particularly struck by the reanalysis of autism (probably biased to Asperger's Syndrome).

"Autistic people classically can’t stand tags on clothing – they find them too scratchy and annoying. Remember the example from Part III about how you successfully predicted away the feeling of the shirt on your back, and so manage never to think about it when you’re trying to concentrate on more important things?

"Autistic people can’t do that as well. Even though they have a layer in their brain predicting “will continue to feel shirt”, the prediction is too precise; it predicts that next second, the shirt will produce exactly the same pattern of sensations it does now. But realistically as you move around or catch passing breezes the shirt will change ever so slightly – at which point autistic people’s brains will send alarms all the way up to consciousness, and they’ll perceive it as “my shirt is annoying”.

Or consider the classic autistic demand for routine, and misery as soon as the routine is disrupted. Because their brains can only make very precise predictions, the slightest disruption to routine registers as strong surprisal, strong prediction failure, and “oh no, all of my models have failed, nothing is true, anything is possible!”

"Compare to a neurotypical person in the same situation, who would just relax their confidence intervals a little bit and say “Okay, this is basically 99% like a normal day, whatever”. It would take something genuinely unpredictable – like being thrown on an unexplored continent or something – to give these people the same feeling of surprise and unpredictability.

"This model also predicts autistic people’s strengths. We know that polygenic risk for autism is positively associated with IQ. This would make sense if the central feature of autism was a sort of increased mental precision. It would also help explain why autistic people seem to excel in high-need-for-precision areas like mathematics and computer programming."

Clark's model also has suggestive things to say about schizophrenia and dreaming.

The idea that most of sensorimotor cognition is an interweaving of bottom-up sensor feature-extraction and top-down model-driven sensory-motor prediction is extremely persuasive and seems a shoo-in for exploitation by artificial neural network research. The architecture of the first round of AGIs seems to be emerging.

One thing not obviously accounted for is that great mystery: consciousness.

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Surfing Uncertainty is on my 'to read' list and you'll get impressions later..